The Scripps Research Institute
Dr. Dorit Trudler is a postdoctoral research associate at The Scripps Research Institute in Dr. Stuart Lipton's group in La Jolla, who is studying the role of immune activation in neurodegenerative and neurodevelopmental disorders. As a graduate student at Tel Aviv University, under the supervision of Dr. Dan Frenkel, Dr. Trudler showed that dysfunction in Parkinson’s disease-related genes leads to a pro-inflammatory and neurotoxic phenotype, which exacerbates disease progression. As a postdoctoral research associate, Dr. Trudler is using human induced pluripotent stem cells (hiPSCs) to model neurological disorders to study neurotoxicity, neuroimmunology, and microglial cell activity. Her most recent work uses hiPSC-derived microglia to study the role of neuroinflammation in misfolded protein disorders, such as Alzheimer’s and Parkinson’s disease.
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