Neuropsychiatric Disorders in Adults and Children: Approach to the Diagnosis and Potential for Precision Behavioral Neurology

Date/Time: Monday, October 18, 2021 - 11:15 AM – 12:45 PM
Track: Interactive Workshop
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In adults and children, the initial symptoms of autoimmune encephalitides may mimic depression, schizophrenia, or bipolar disorder. Distinguishing these mechanisms is essential to provide timely and effective treatment. For the autoimmune encephalitides, advances in diagnosis have resulted from the identification of new antibodies and a greater understanding of the cellular mechanisms of neurologic injury. For psychiatric disorders, new genomic discoveries offer the potential to provide precision psychiatric care based on specific disease mechanisms. This session will discuss the approach to diagnostic evaluation of children and adults who present with the new onset of neuropsychiatric symptoms, with a specific focus on the characteristics of autoimmune encephalitides. The session will address the mechanisms of antibody-mediated neuronal dysfunction and different clinical phenotypes in adults and children. This session will also cover recent advances in psychiatric genomics and the implications of this research for targeted treatment. The overall goals of the session are to improve the early recognition of autoimmune encephalitis for patients who may present to a neurologist with symptoms of a psychiatric disorder and to gain awareness of the advances in psychiatric genomics with implications for behavioral neurology.

Chair: Mark Wainwright, MD, PhD



  • Understand the differences in neuropsychiatric symptoms in the presentation of autoimmune encephalitis in adults and children and approach to diagnostic evaluation in different age groups

  • Understand the mechanisms of cognitive impairment and psychiatric symptoms resulting from anti-neuronal antibodies and the implications for treatment

  • Understand the emerging uses of psychiatric genomics and its potential applications for molecular diagnostics and treatment in neuropsychiatric disorders

Advances in Neuropsychiatric Genomics

Time: 11:15 AM – 12:45 PM


Mechanisms of Antibody Mediated Cognitive Impairment

Time: 11:15 AM – 12:45 PM

Neuropsychiatric Characteristics of Autoimmune Encephalitis in Adults and Children

Time: 11:15 AM – 12:45 PM