ANA-AHS Headache

*You must be registered for the ANA2021 Virtual Annual Meeting to access the live SIG Series sessions.

Date/Time ET: Monday, November 1, 2021 - 11:30 AM  – 1:00 PM

Session Title: Emerging Concepts in Migraine Pathophysiology

Description: Headache is the second to third leading cause of global years lived with disability. Migraine headaches represent one of the most disabling headache diagnoses, affecting 12% of the general population. The economic and social impact of migraine, particularly in women, highlight the need to better understand mechanisms involved in migraine headache generation and its accompanying symptoms. Basic science and clinical research in migraine have culminated in new translational targets, providing renewed hope for migraine patients. Despite these recent advances, there are still many unanswered questions about disease mechanism. The focus of this session is to highlight emerging discoveries in migraine research that increase our understanding of the biological mechanisms of trigeminal pain, cortical events involved in migraine aura and accompanying incapacitating symptoms like light sensitivity.

Chair: William Renthal, MD, PhD, Brigham and Women’s Hospital, Harvard Medical School

Co-Chair: Andrea Harriott, MD, PhD, Massachusetts General Hospital

At the end of this activity, participants will be able to:

  • Discuss pathophysiological mechanisms of migraine
  • Identify emerging concepts from preclinical migraine models
  • Describe mechanisms involved in accompanying features of migraine including photophobia


Non-Canonical Glutamate Signaling and Migraine: Emerging Concepts in Cortical Hyperexcitability


KC Brennan, MD

University of Utah

The Role of Neuronal Complexity and HDAC6 in Models of Chronic Migraine


Amynah Pradhan, PhD

University of Illinois at Chicago

The Role of Intrinsically Photosensitive Retinal Ganglion Cells in Photophobia


Eric Kaiser, MD, PhD

University of Pennsylvania

A Midbrain Circuit That Mediates Headache Aversiveness in Rats


Maggie Wuang, MD, PhD

University of California, San Francisco

Efferent Projections of Cgrp/Calca-expressing Parabrachial Neurons in Mice

Oral Presenter:

Dake Huang, BS

University of Iowa

Continuing Medical Education

The American Neurological Association hosts a wide range of educational programs. These programs seek to enhance the development and success of those pursuing a career in academic neurology at all levels. There are educational offerings to benefit those at the beginning stages of their careers, including students and those in their first faculty position, as well as those looking for best practices in Chair level positions. These programs seek to enhance attendee success in the field of academic neurology and to contribute to the overall education of neurologists and neuroscientists.

The Special Interest Groups offer CME to eligible participants. Click here to see a complete breakdown of how many credits are available per session.

ACCME Accreditation, AMA Designation, and MIPS Statements **Pertaining to Each Session Awarding CME**

The American Neurological Association is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians.

The American Neurological Association designates this live activity for a maximum of 1.5 AMA PRA Category 1 Credit(s)™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

Completion of this accredited CME activity meets the expectations of an Accredited Safety or Quality Improvement Program (IA_PSPA_28) for the Merit-based Incentive Payment Program (MIPS).


Instructions For Obtaining CME

Following the event, the evaluation and credit claiming system will open in OnDEC. Please complete the online evaluation by 12/31/2021 to obtain CME credit. You will be provided with a certificate after completing the evaluation. If you have any questions, please contact the ANA Meeting Coordinator at:

Click here to see a complete breakdown of how many credits are available per session.

Financial Disclosure Statements

The planners and faculty for this activity do not have any relationships to disclose unless listed here. Any relevant relationships with ACCME-defined ineligible companies will be mitigated according to ACCME Standards prior to the start of the activity.

Disclosure of Commercial Support

ANA received educational grants from the following ACCME-defined ineligible companies to support the CME aspects of this event: Added as confirmed.

DISCLAIMER: The ANA does not endorse or affiliate with third-party companies, products or services including those that may have elected to support the Special Interest Groups.